On the Tear Resistance of Skin
Scientists quantified the extreme tear resistance of skin and identified the underlying structural features, which lead to its sophisticated failure mechanisms. They expressed the deformation in terms of four mechanisms of collagen fibril activity in skin under tensile loading that virtually eliminate the possibility of tearing in pre-notched samples. [Nat Commun] Full Article
Emerging Properties of Adhesion Complexes: What Are They and What Do They Do?
The regulation of cell adhesion machinery is central to a wide variety of developmental and pathological processes and occurs primarily within integrin-associated adhesion complexes. The authors review recent advances that have furthered our understanding of the composition, organization, and dynamics of these complexes, and provide an updated view on their emerging functions. [Trends Cell Biol] Abstract
UC Researchers Awarded Stem Cell Grants
University of California (UC) researchers from two campuses received three grants totaling more than $12 million in funding from the state’s stem cell agency to develop stem cell treatments for Huntington’s disease, spina bifida and chronic diabetic wounds. [UC Health] Press Release