Cysteine Cathepsins and Extracellular Matrix Degradation|
This review focuses on cysteine cathepsins and their extracellular functions linked with ECM degradation, including regulation of their activity, which is often enhanced by acidification of the extracellular microenvironment, such as found in the bone resorption lacunae or tumor microenvironment. [Biochim Biophys Acta]
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